The Link Between Psilocybin and Mental Health

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Psilocybin is a psychedelic compound that can produce altered states of consciousness, including euphoria and hallucinations. It’s the main active ingredient in “magic mushrooms.”

A study published in the Journal of Psychopharmacology found that psilocybin-assisted therapy could help people with treatment-resistant depression. The trial involved 29 patients who had not improved after at least two other treatments. After one to three sessions with a therapist, all but six showed significant improvement in their symptoms for up to five weeks after receiving the drug or placebo.

Read on to learn more about the link between psilocybin and mental health.

What is Psilocybin

Psilocybin is a psychedelic compound that can produce altered states of consciousness, including euphoria and hallucinations. It’s the main active ingredient in “magic mushrooms.”

It works by binding to a receptor for the neurotransmitter serotonin in certain parts of the brain. This leads to changes in perception, thought, and mood that people may experience as hallucinations or a change in their sense of time.

A DEA fact sheet states that a typical dose of psilocybin is about 0.2 grams, and its effects last from four to eight hours.


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How it can help with depression and anxiety

Recent studies have also shown that psilocybin can help treat depression and anxiety. Researchers have discovered that the drug reduces activity in certain parts of the brain that are overactive in depression, such as the anterior cingulate cortex.

Reports show that patients who have undergone psilocybin-assisted therapy had a significant reduction in depression and anxiety. The findings suggest that psilocybin may help to alleviate symptoms of depression by acting on receptors for the neurotransmitters serotonin, norepinephrine, and dopamine. These chemicals are linked with mood regulation.

A study by Johns Hopkins Medicine

In a study conducted by Johns Hopkins Medicine, cancer patients reported decreased anxiety and depression for up to six months after one psilocybin session.

This is super interesting because I am currently dealing with clinical depression and have been on and off therapy for the past year. It’s nice to see other options besides medication, which always seems to work for a little while and then stop.

The government of Canada has LEGALISED mushrooms for end-of-life cases, so that’s a start!=

Why you should use psilocybin if you are depressed or anxious, even if it’s just recreationally to start with

A good trip can help you in your everyday life by showing how you can be happy without any drugs or alcohol. This awareness and happiness will stay with you after the trip ends and show that drugs are not needed for a good time.

A bad trip can be just as beneficial. One of the main benefits is that the trip can help you to resolve issues from your past. The psychedelic state bypasses your ego and allows for more creativity, allowing you to talk about things you would not normally talk about.

I think people should start with just recreational doses because it will give them a chance to get used to the feeling of mushrooms and work up to a therapeutic dose that will be effective for their specific condition.

Psilocybin to treat addiction

Using a drug to counter the addictive effects of another may seem counterintuitive, but one study found that psilocybin might be able to do just that.

In the Johns Hopkins experiment, participants were given several doses of psilocybin over two months while undergoing therapy for their alcohol addiction. The team assessed the severity of each participant’s addiction both before and after receiving the drug treatment using a standard questionnaire.

The study found that the participants had an average drop in their addiction score of 30%. The effects of psilocybin, specifically “mystical experience,” were linked to this decrease.

Further studies showed similar results and confirmed that psilocybin could help treat alcohol addictions.

Using psychedelics spiritually or artistically

The explosion in popularity of these substances in the 60s and 70s was partly due to people using psychedelics for more than just a buzz. A growing number of psychonauts (self-described adventurers of the mind) are turning to psychedelics such as psilocybin, LSD, or DMT to push their creativity, treat depression, ease anxiety, and much more.

Health is more than just a physical or mental thing. You need fulfillment in order to be healthy. We need that in some way. And psychedelics can really provide you with that, at least temporarily.

Improved Social interactions

Psychedelics have been known to cause changes in one’s personality and behavior after a trip. The fact that the chemical balance in your brain is altered can bring out aspects of your personality you didn’t know were there before or change how you act to other people.

Finding yourself able to let go of past grudges or inhibitions could help with social interaction and allow you to be more open with both your entourage and strangers.

 Potential side effects that could happen when taking the drug

The main potential side effect is having a bad trip, which can include fear and anxiety. However, this happens in less than 20% of cases.

To get the most out of the drug, you should set a positive environment with people you trust before taking it. This way, you will be able to discuss your thoughts and feelings about your experience afterward.


Depression is a mental disorder that affects many people and can be hard to treat. New research suggests that taking psilocybin-based treatments could help patients recover from depression more quickly, which is promising for those struggling with this debilitating condition.

If you’re looking for relief from your own depression symptoms or want to learn about the potential benefits of psilocybin in treating mental health conditions like anxiety disorders and PTSD, reach out today so we can talk through our options together!

Our team has plenty of experience working with individuals suffering from mood disorders and will work closely with you every step of the way on your journey into wellness. Start your journey in the mind today with our huge selection of magic mushrooms available at competitive prices online now!

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